Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439730 | 1.00 | EPHX1 (0.44) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL305154 | 0.98 | EPHX1 (0.41) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL697832 | 0.94 | EPHX1 (0.37) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL8693054 | 0.89 | — | — | |
| SCHEMBL5014635 | 0.81 | EPHX1 (0.44) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL5011343 | 0.81 | EPHX1 (0.44) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL73777 | 0.80 | KAT2B (0.36) | — | |
| SCHEMBL13387598 | 0.79 | EPHX1 (0.60) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL984315 | 0.79 | EPHX1 (0.60) | EPHX1NAAAHTTCYP2C19CA12 | |
| SCHEMBL8426647 | 0.79 | EPHX1 (0.60) | EPHX1NAAAHTTCYP2C19CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4646 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192298-A | Preparation method of sartan drug intermediate | 上海科胜药物研发有限公司 | 2025-06-24 | — | — | CN | claimed |
| CN-120053663-A | Pharmaceutical use of SP/KLF transcription factor inhibitors in combination with deacetylase inhibitors | 天津医科大学 | 2025-05-30 | — | — | CN | claimed |
| CN-116575244-B | Flax health-preserving enzyme preparation and preparation method and application thereof | 江苏尼美达科技有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119732761-A | Invisible appliance for treating periodontal disease and preventing tooth enamel demineralization and preparation method thereof | 首都医科大学附属北京口腔医院 | 2025-04-01 | — | — | CN | claimed |
| CN-119499379-A | Pharmaceutical application of ELANE gene as heart failure target and new application of ciliristat | 广东医科大学 | 2025-02-25 | — | — | CN | claimed |
| CN-119371408-A | Amorphous alisrtan medoxomil and preparation method thereof | 安徽艾立德制药有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119367359-A | Axiartan ester composition and preparation method thereof | 济南舜景医药科技有限公司 | 2025-01-28 | — | — | CN | claimed |
| CN-222174072-U | Reaction kettle for producing sarcandesartan sodium | 山东科源制药股份有限公司 | 2024-12-17 | — | — | CN | claimed |
| CN-119081962-A | Marine Dechang active coccus and application thereof in degrading cilexetil under high-salt condition | 辽宁省海洋水产科学研究院(辽宁省农业科学院大连生物技术研究所、辽宁省海洋环境监测总站) | 2024-12-06 | — | — | CN | claimed |
| CN-119061553-A | Production process of tencel hemp core-spun weft elastic non-ironing woven fabric | 鲁泰纺织股份有限公司 | 2024-12-03 | — | — | CN | claimed |
| EP-0497978-A1 | CEPHALOSPORIN COMPOUNDS AND PRODUCTION THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 1992-08-12 | — | — | EP | claimed |
| EP-0484966-A2 | 7-Acyl-3-(substituted carbamoyloxy) cephem compounds, use thereof and process for their preparation | Eisai Co., Ltd. (JP) | 1992-05-13 | — | — | EP | claimed |
| WO-1992003443-A1 | ANTIBACTERIAL PENEM COMPOUNDS | SUNTORY LIMITED (JP) | 1992-03-05 | — | — | WO | claimed |
| WO-1991013054-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1991-09-05 | — | — | WO | claimed |
| US-4975444-A | INHIBITORS OF ANGIORENSIN-CONVERTING ENZYME AS WELL AS A ENDOPEPTIDASE; CARDIOTONIC AGENTS; GLAUCOMA; DIURETICS | PFIZER INC. (US) | 1990-12-04 | — | — | US | claimed |
| EP-0358398-A1 | Cycloalkyl-substituted glutaramide antihypertensive agents | Pfizer Limited (GB) | 1990-03-14 | — | — | EP | claimed |
| US-4874856-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-10-17 | — | — | US | claimed |
| EP-0307872-A2 | Esters of amino-acids, process for their preparation, medicaments containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-22 | — | — | EP | claimed |
| EP-0304036-A2 | 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof | Bristol-Myers Squibb Company (US) | 1989-02-22 | — | — | EP | claimed |
| US-4731362-A | Alkylcarbamoyloxymethylcephem compounds | SHIONOGI & CO., LTD. (JP) | 1988-03-15 | — | — | US | claimed |