Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323513 | 0.86 | CSNK2A2 (0.71) | CA1CA2KDM4EUSP2ABCG2 | |
| SCHEMBL18810398 | 0.85 | GSK3B (0.78) | CA1CA2KDM4EKMT2ACSNK2A2 | |
| SCHEMBL269558 | 0.85 | CA1 (0.88) | CA1CA2KDM4ENPC1RAB9A | |
| SCHEMBL16604876 | 0.85 | CA1 (0.88) | CA1CA2KDM4ENPC1RAB9A | |
| SCHEMBL1429971 | 0.85 | NPC1 (0.60) | KDM4EABCG2NPC1RAB9AKMT2A | |
| SCHEMBL12798151 | 0.84 | CSNK2A2 (0.73) | CA1CA2KDM4EUSP2ABCG2 | |
| SCHEMBL12918700 | 0.84 | TDP1 (0.65) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9422430 | 0.84 | CA1 (0.65) | CA1CA2KDM4ENPC1RAB9A | |
| SCHEMBL5202186 | 0.84 | NPC1 (0.68) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7320882 | 0.84 | MAPT (0.61) | KDM4ENPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1240713-C | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-02-08 | — | — | CN | disclosed |
| CN-1296494-A | New compound | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |