Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 2/20 | 0.63 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25540903 | 0.96 | KLK7 (0.67) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL2329138 | 0.96 | KLK7 (0.67) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL2329143 | 0.96 | KLK7 (0.67) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL9496190 | 0.95 | KLK7 (0.61) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL25932586 | 0.94 | MAPT (0.60) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL11982665 | 0.94 | KLK7 (0.58) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL3826731 | 0.94 | KLK7 (0.60) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL24130643 | 0.93 | KLK7 (0.59) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL24130639 | 0.93 | KLK7 (0.59) | KLK7KLK5MAPTCA1CA2 | |
| SCHEMBL7316805 | 0.93 | MAPT (0.64) | KLK7KLK5MAPTSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024094098-A1 | COMPOUND FOR DELIVERY SYSTEM AND USE THEREOF | 益杰立科(上海)生物科技有限公司 | 2024-05-10 | — | — | WO | disclosed |
| US-4691007-A | HUMAN LEUKOCYTE ELASTASE INHIBITORS | ICI AMERICAS INC. (US) | 1987-09-01 | — | — | US | disclosed |
| US-4596789-A | Pharmaceuticals | ICI AMERICAS INC. (US) | 1986-06-24 | — | — | US | disclosed |
| EP-0124317-A2 | Proline derivatives | ICI AMERICAS INC. (US) | 1984-11-07 | — | — | EP | disclosed |