Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.71 |
| ▸ | ACE | P12821 | 1/20 | 0.68 |
| ▸ | ECE1 | P42892 | 1/20 | 0.68 |
| ▸ | XRCC6 | P12956 | 1/20 | 0.63 |
| ▸ | XRCC5 | P13010 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320703 | 0.89 | PRKDC (0.68) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL7320140 | 0.83 | PRKDC (0.71) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL31061328 | 0.83 | PRKDC (1.00) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL3533604 | 0.83 | PRKDC (1.00) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL3536375 | 0.81 | PRKDC (1.00) | PRKDC | |
| SCHEMBL3361567 | 0.81 | PRKDC (1.00) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL30218216 | 0.81 | PRKDC (1.00) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL13435723 | 0.80 | PRKDC (0.81) | PRKDCACEECE1XRCC6XRCC5 | |
| SCHEMBL31061046 | 0.80 | PRKDC (1.00) | PRKDC | |
| SCHEMBL3536694 | 0.80 | PRKDC (1.00) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | claimed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | disclosed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | disclosed |