Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.72 |
| ▸ | DPP4 | P27487 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3530109 | 0.85 | EPHX2 (0.60) | EPHX2DPP4ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL10487752 | 0.80 | EPHX2 (0.51) | EPHX2DPP4ALDH1A1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL11125308 | 0.79 | EPHX2 (0.50) | EPHX2DPP4ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL11102473 | 0.79 | EPHX2 (0.64) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5988119 | 0.76 | DPP4 (0.55) | EPHX2DPP4ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL7432375 | 0.76 | EPHX2 (0.49) | EPHX2DPP4FAPDPP7MGAM | |
| Hydrochloric Acid SCHEMBL5987777 | 0.75 | DPP4 (0.54) | EPHX2DPP4ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL22175134 | 0.74 | EPHX2 (0.44) | EPHX2ALDH1A1TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15816701 | 0.73 | EPHX2 (0.43) | EPHX2ALDH1A1MGAMGAASI | |
| SCHEMBL12953539 | 0.73 | EPHX2 (0.54) | EPHX2ALDH1A1MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221665-A | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0369391-A2 | N-substituted amides | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4820729-A | N-substituted-amido-amino acids | RORER PHARMACEUTICAL CORPORATION (US) | 1989-04-11 | — | — | US | disclosed |