SCHEMBL732522

SCHEMBL732522

CC(O)=C(C)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3191000 1.00
SCHEMBL28777646 0.96
SCHEMBL30659815 0.81
SCHEMBL30608062 0.81
SCHEMBL11512484 0.79
SCHEMBL9961321 0.79
SCHEMBL11880052 0.79
SCHEMBL11273556 0.72
SCHEMBL11134144 0.72
SCHEMBL8172618 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421473-B1 METHOD FOR PREPARING PYRROLOPYRIMIDINE COMPOUNDS AND APPLICATION THEREOF CINKATE PHARM TECH SHANGHAI CO LTD (CN) 2022-03-30 EP claimed
US-11591333-B2 Substituted pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors CINAKATE PHARM TECH (SHANGHAI) CO., LTD. (CN) 2023-02-28 US disclosed
EP-3421473-B1 METHOD FOR PREPARING PYRROLOPYRIMIDINE COMPOUNDS AND APPLICATION THEREOF CINKATE PHARM TECH SHANGHAI CO LTD (CN) 2022-03-30 EP disclosed
US-8324420-B2 Process for producing acrylonitrile compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-12-04 US disclosed
US-8138368-B2 Process for producing acrylonitrile compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-20 US disclosed
US-20110313173-A1 Process for producing acrylonitrile compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-12-22 US disclosed
US-20100029951-A1 Process for producing acrylonitrile compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-02-04 US disclosed
US-7649104-B2 producing 3-acyloxyacrylonitrile compound as an agricultural and horticultural pesticide; using the produced 3-oxopropionitrile compound as the intermediate NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-01-19 US disclosed
US-20100010035-A1 Novel Dual Action Receptors Antagonists (Dara) at the Ati and Eta Receptors TORRENT PHARMACEUTICALS LTD. (IN) 2010-01-14 US disclosed
EP-1996588-A1 NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS Torrent Pharmaceuticals Ltd (IN) 2008-12-03 EP disclosed
WO-2007100295-A1 NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS TORRENT PHARMACEUTICALS LTD (IN) 2007-09-07 WO disclosed