Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330569 | 0.84 | RCE1 (0.44) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL360511 | 0.83 | TSHR (0.48) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL7332513 | 0.82 | CYP2D6 (0.50) | TSHRMAPTCYP2D6TRPA1SLC6A2 | |
| SCHEMBL27700953 | 0.82 | MAPT (0.54) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL1942288 | 0.79 | TSHR (0.44) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL4970198 | 0.79 | RCE1 (0.46) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL23998026 | 0.78 | TSHR (0.48) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL14001693 | 0.78 | MAPT (0.58) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL20463639 | 0.78 | RCE1 (0.49) | TSHRMAPTIDO1SLC1A3SLC1A2 | |
| SCHEMBL5018878 | 0.78 | RCE1 (0.49) | TSHRMAPTIDO1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |
| US-4140702-A | Process for producing vitamin E intermediate compounds | HOFFMANN-LA ROCHE INC. (US) | 1979-02-20 | — | — | US | disclosed |