Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.72 |
| ▸ | PRKDC | P78527 | 4/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.50 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322397 | 0.86 | P2RY12 (0.70) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7320092 | 0.83 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7316704 | 0.80 | P2RY12 (0.64) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7318851 | 0.80 | P2RY12 (0.64) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7324120 | 0.80 | P2RY12 (0.56) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7321791 | 0.79 | P2RY12 (0.71) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7320782 | 0.79 | P2RY12 (0.58) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB | |
| SCHEMBL7324297 | 0.77 | P2RY12 (1.00) | P2RY12 | |
| SCHEMBL7326225 | 0.75 | P2RY12 (0.69) | P2RY12PRKDC | |
| SCHEMBL7326734 | 0.73 | P2RY12 (0.82) | P2RY12PRKDCPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | claimed |
| EP-0459983-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | PHARMACIA & UPJOHN COMPANY (US) | 1991-12-11 | — | — | EP | claimed |
| WO-1990006921-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 1-BENZOPYRAN-4-ONES AND 2-AMINO-1,3-BENZOXAZINE-4-ONES | THE UPJOHN COMPANY (US) | 1990-06-28 | — | — | WO | claimed |
| US-5703075-A | Antiatherosclerotic and antithrombotic 1-benzopyran-4-ones and 2-amino-1,3-benzoxazine-4-ones | PHARMACIA & UPJOHN COMPANY (US) | 1997-12-30 | — | — | US | disclosed |