Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 9/20 | 0.56 |
| ▸ | CTSD | P07339 | 10/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | PGC | P20142 | 1/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322824 | 0.96 | BACE1 (0.55) | BACE1CTSDELANE | |
| SCHEMBL7320854 | 0.96 | BACE1 (0.55) | BACE1CTSDELANE | |
| SCHEMBL7331111 | 0.96 | BACE1 (0.55) | BACE1CTSDELANE | |
| SCHEMBL9754554 | 0.96 | BACE1 (0.55) | BACE1CTSDELANE | |
| SCHEMBL10378717 | 0.93 | BACE1 (0.58) | BACE1CTSDHRH1CTSEPGC | |
| SCHEMBL7329186 | 0.93 | BACE1 (0.58) | BACE1CTSDHRH1CTSEPGC | |
| SCHEMBL7322772 | 0.87 | BACE1 (0.48) | BACE1CTSDCTSEPGC | |
| SCHEMBL7322940 | 0.84 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL7322713 | 0.84 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL7322882 | 0.84 | BACE1 (0.45) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |