Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.64 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.48 |
| ▸ | CHRNG | P07510 | 2/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.48 |
| ▸ | CHRND | Q07001 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9785786 | 0.92 | GRIA1 (0.57) | GRIA1GRIA3CA12CA1CA2 | |
| SCHEMBL9785902 | 0.85 | GRIA1 (0.60) | GRIA1GRIA3CA12CA1CA2 | |
| SCHEMBL7321088 | 0.84 | CA12 (0.70) | GRIA1GRIA3CA12CA1CA2 | |
| Acetic Acid SCHEMBL9785792 | 0.81 | GRIA1 (0.56) | GRIA1GRIA3CHRNA1CHRNGCHRNB1 | |
| SCHEMBL29998508 | 0.81 | GRIA1 (0.98) | GRIA1GRIA3GRIA2GRIA4CHRNA1 | |
| SCHEMBL398742 | 0.81 | CHRNA1 (0.64) | GRIA1CA12CA1CA2CA3 | |
| Joro Spider Toxin 3 SCHEMBL13151444 | 0.80 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4 | |
| Joro Spider Toxin 3 SCHEMBL28731031 | 0.80 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4 | |
| SCHEMBL29561626 | 0.80 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4 | |
| Joro Spider Toxin 3 SCHEMBL29412442 | 0.80 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0361687-B1 | Therapeutic polyamine-amides | BRITISH TECH GROUP (GB) | 1993-10-27 | — | — | EP | disclosed |
| US-5218000-A | Nervous system disorders, antiischemic agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1993-06-08 | — | — | US | disclosed |
| EP-0361687-A1 | Therapeutic polyamine-amides | BTG INTERNATIONAL LIMITED (GB) | 1990-04-04 | — | — | EP | disclosed |
| WO-1990002114-A1 | THERAPEUTIC POLYAMINE-AMIDES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1990-03-08 | — | — | WO | disclosed |