Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273731 | 1.00 | POLB (0.39) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL1933031 | 1.00 | POLB (0.39) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL7325409 | 1.00 | POLB (0.39) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL7280473 | 1.00 | POLB (0.39) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL2371479 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL9112735 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL2371475 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL19526286 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL2370535 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 | |
| SCHEMBL2371471 | 0.82 | GABRR1 (0.48) | POLBALDH1A1LMNAGABRR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384380-B1 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC (JP) | 1996-06-19 | — | — | EP | disclosed |
| US-5151497-A | Central nervous system disorders, antidepressants, epilepsy and cognition activators | JAPAN TOBACCO INC. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0384380-A2 | Novel peptide derivatives and their pharmaceutical use | JAPAN TOBACCO INC. (JP) | 1990-08-29 | — | — | EP | disclosed |