Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | HTR7 | P34969 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928970 | 0.88 | HTR2A (0.72) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL14318600 | 0.87 | HTR2A (0.81) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL11107232 | 0.84 | HTR2A (0.68) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL9879782 | 0.84 | HTR2A (0.63) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL8714691 | 0.83 | HTR2A (0.74) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL9499649 | 0.83 | SMN1; SMN2 (0.69) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL14636954 | 0.83 | SMN1; SMN2 (0.69) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL14282300 | 0.83 | HTR2A (0.66) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| SCHEMBL10928975 | 0.82 | HTR2A (0.72) | HTR2AHTR2CHTR7HTR6HSD11B1 | |
| Hydrochloric Acid SCHEMBL9502312 | 0.82 | SMN1; SMN2 (0.67) | HTR2AHTR2CHTR7HTR6HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377528-B1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA (FR) | 1993-12-08 | — | — | EP | claimed |
| US-5001134-A | Piperidines, processes of preparation and medications containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1991-03-19 | — | — | US | claimed |
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | claimed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | claimed |
| WO-2000024715-A1 | PIPERIDINE COMPOUNDS AND THEIR USE IN THE POPULATION CONTROL OF RODENTS AND OTHER VERTEBRATE PESTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-05-04 | — | — | WO | disclosed |
| US-5001134-A | Piperidines, processes of preparation and medications containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1991-03-19 | — | — | US | disclosed |
| US-5001134-A | Piperidines, processes of preparation and medications containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1991-03-19 | — | — | US | disclosed |
| EP-0377528-A1 | Piperidines, process for their preparation and pharmaceutical compounds containing them | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1990-07-11 | — | — | EP | disclosed |
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-4032642-A | SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-06-28 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |
| US-3956296-A | ANTIINFLAMMATORY, SEDATIVES, TRANQUILIZERS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1976-05-11 | — | — | US | disclosed |