Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 2/20 | 0.56 |
| ▸ | CTSC | P53634 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30924826 | 0.92 | MME (0.65) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL11211282 | 0.92 | MME (0.65) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL11211279 | 0.92 | MME (0.65) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL30735714 | 0.88 | MME (0.60) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL31215125 | 0.88 | MME (0.60) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL31215069 | 0.86 | MME (0.59) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL30595093 | 0.86 | MME (0.59) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL29892331 | 0.85 | MME (0.58) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL31096839 | 0.84 | MME (0.56) | MMECTSCALPIPKMPTGS1 | |
| SCHEMBL30567413 | 0.84 | MME (0.67) | MMECTSCALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272671-A2 | Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors | SANDOZ LTD. (CH) | 1988-06-29 | — | — | EP | disclosed |