⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11116606 | 0.84 | — | — | |
| SCHEMBL11801942 | 0.84 | — | — | |
| SCHEMBL14660888 | 0.83 | — | — | |
| SCHEMBL14058847 | 0.83 | — | — | |
| SCHEMBL8481980 | 0.83 | — | — | |
| SCHEMBL14058846 | 0.83 | — | — | |
| SCHEMBL2184592 | 0.81 | ACACB (0.32) | — | |
| SCHEMBL7288407 | 0.81 | ACACB (0.32) | — | |
| SCHEMBL4589893 | 0.80 | ACACB (0.34) | — | |
| SCHEMBL7614125 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5140009-A | Stable against proteolytic enzymes; anticarcinogenic agents; urogenital disorders | TAP PHARMACEUTICALS, INC. (US) | 1992-08-18 | — | — | US | claimed |
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | claimed |
| EP-0417454-A2 | Reduced size LHRH analogs | ABBOTT LABORATORIES (US) | 1991-03-20 | — | — | EP | claimed |
| EP-0400065-A4 | LHRH ANALOGS | — | 1991-03-13 | — | — | EP | claimed |
| EP-0413209-A1 | LHRH analogs | TAP Pharmaceuticals Inc. (US) | 1991-02-20 | — | — | EP | claimed |
| EP-0400065-A1 | LHRH ANALOGS. | ABBOTT LAB (US) | 1990-12-05 | — | — | EP | claimed |
| WO-1989007450-A1 | LHRH ANALOGS | ABBOTT LABORATORIES (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0328090-A2 | LHRH analogs | ABBOTT LABORATORIES (US) | 1989-08-16 | — | — | EP | claimed |
| WO-1987005302-A1 | NOVEL RENIN-INHIBITING PEPTIDES HAVING A DIHYDROXYETHYLENE ISOSTERE TRANSITION STATE INSERT | THE UPJOHN COMPANY (US) | 1987-09-11 | — | — | WO | claimed |
| EP-0438311-A2 | Di- and tripeptide renin inhibitors | MERCK & CO. INC. (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0289506-A4 | LIPOXYGENASE INHIBITORS | — | 1990-12-12 | — | — | EP | disclosed |
| EP-0289506-A1 | LIPOXYGENASE INHIBITORS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-11-09 | — | — | EP | disclosed |
| WO-1988003800-A1 | LIPOXYGENASE INHIBITORS | CHEMEX PHARMACEUTICALS, INC. (US) | 1988-06-02 | — | — | WO | disclosed |
| US-4708964-A | Lipoxygenase inhibitors | CHEMEX PHARMACEUTICALS (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0126344-A2 | Tripeptide esters of therapeutic agents | ABBOTT LABORATORIES (US) | 1984-11-28 | — | — | EP | disclosed |