Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189896 | 0.88 | KMT2A (0.55) | ALDH1A1KMT2ARAB9AGLAKDM4E | |
| SCHEMBL28899278 | 0.88 | KMT2A (0.55) | ALDH1A1KMT2ARAB9AGLAKDM4E | |
| SCHEMBL4387733 | 0.88 | KMT2A (0.55) | ALDH1A1KMT2ARAB9AGLAKDM4E | |
| SCHEMBL4385603 | 0.86 | KMT2A (0.52) | ALDH1A1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4389072 | 0.85 | KMT2A (0.53) | ALDH1A1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL4392704 | 0.84 | PSEN1 (0.58) | ALDH1A1KMT2ACYP2C19RAB9AGLA | |
| SCHEMBL4315505 | 0.83 | KMT2A (0.52) | ALDH1A1KMT2AMAPTGLAKDM4E | |
| SCHEMBL4064196 | 0.83 | KMT2A (0.53) | ALDH1A1KMT2AGLAKDM4ELMNA | |
| SCHEMBL4064197 | 0.83 | KMT2A (0.53) | ALDH1A1KMT2AGLAKDM4ELMNA | |
| SCHEMBL288165 | 0.83 | USP2 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204268-B1 | CYCLIC DIAZA COMPOUNDS | COR THERAPEUTICS, INC | 2001-03-20 | — | — | US | disclosed |
| EP-0977772-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998046626-A1 | SELECTIVE FACTOR Xa INHIBITORS | COR THERAPEUTICS, INC. (US) | 1998-10-22 | — | — | WO | disclosed |