SCHEMBL7326432

SCHEMBL7326432

COc1cc(OCCNc2ccncc2)cc(S(=O)(=O)N(C)c2ccccc2)c1

nearest known ligand 0.80

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F2 P00734 18/20 0.80
L3MBTL1 Q9Y468 1/20 0.50
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8541024 0.92 F2 (0.78) F2L3MBTL1
SCHEMBL8546878 0.89 F2 (1.00) F2
SCHEMBL8547209 0.88 F2 (0.88) F2L3MBTL1
SCHEMBL8547842 0.86 F2 (0.67) F2
SCHEMBL8547694 0.83 F2 (1.00) F2L3MBTL1
Hydrochloric Acid SCHEMBL8543470 0.82 F2 (0.98) F2L3MBTL1
SCHEMBL8544377 0.82 F2 (0.77) F2
SCHEMBL7333893 0.82 KMT2A (0.68) F2MEN1KMT2A
SCHEMBL8544805 0.82 F2 (0.78) F2L3MBTL1
SCHEMBL8545533 0.78 F2 (0.85) F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0687253-B1 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME BOEHRINGER MANNHEIM GMBH (DE) 1998-12-16 EP disclosed
EP-0687253-A1 NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME Roche Diagnostics GmbH (DE) 1995-12-20 EP disclosed
WO-1994020467-A1 NEW 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME BOEHRINGER MANNHEIM GMBH (DE) 1994-09-15 WO disclosed