Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947671 | 0.91 | F2 (0.53) | F2 | |
| SCHEMBL7296054 | 0.88 | F2 (0.52) | F2 | |
| Hydrochloric Acid SCHEMBL8716926 | 0.87 | F2 (0.57) | F2 | |
| Acetic Acid SCHEMBL8947667 | 0.87 | F2 (0.51) | F2 | |
| SCHEMBL7300155 | 0.86 | F2 (0.52) | F2 | |
| Acetic Acid SCHEMBL8719840 | 0.86 | F2 (0.50) | F2 | |
| Hydrochloric Acid SCHEMBL8947689 | 0.86 | F2 (0.47) | F2 | |
| Acetic Acid SCHEMBL8947586 | 0.85 | F2 (0.47) | F2 | |
| Acetic Acid SCHEMBL8947565 | 0.84 | F2 (0.53) | F2 | |
| SCHEMBL9169944 | 0.84 | F2 (0.55) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0559046-B1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| EP-0559046-A1 | N-amidinopiperidinyl(3/4)- or N-amidino-1,4-Oxazinyl(2)-substituted sulfonamides, process for their preparation and use as thrombin inhibitors | F.HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1993-09-08 | — | — | EP | disclosed |