Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8358519 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL21501453 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL21964905 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL2979960 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL19400311 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL14073780 | 0.87 | PAOX (0.56) | MEN1ALDH1A1PLGLMNATHRB | |
| Hydrochloric Acid SCHEMBL8356936 | 0.85 | PAOX (0.54) | MEN1ALDH1A1PLGLMNATHRB | |
| SCHEMBL1875583 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL31657036 | 0.80 | MEN1 (0.52) | MEN1ALDH1A1PLGLMNATHRB | |
| Trifluoroacetic Acid SCHEMBL31657055 | 0.80 | MEN1 (0.52) | MEN1ALDH1A1PLGLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489032-A1 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS. | BRITISH BIO TECHNOLOGY (GB) | 1992-06-10 | — | — | EP | disclosed |
| WO-1991002716-A2 | HYDROXAMIC ACID BASED COLLAGENASE INHIBITORS | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-03-07 | — | — | WO | disclosed |