⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471357 | 0.71 | — | — | |
| SCHEMBL4354135 | 0.70 | — | — | |
| SCHEMBL7253877 | 0.64 | — | — | |
| SCHEMBL5070128 | 0.61 | — | — | |
| SCHEMBL9677469 | 0.60 | — | — | |
| SCHEMBL14367461 | 0.59 | — | — | |
| SCHEMBL12707592 | 0.57 | — | — | |
| SCHEMBL22540229 | 0.57 | — | — | |
| SCHEMBL19446589 | 0.57 | — | — | |
| SCHEMBL13292019 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000510870-A | — | — | 2000-08-22 | — | — | JP | claimed |
| EP-0927166-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | Bayer Corporation (US) | 1999-07-07 | — | — | EP | claimed |
| WO-1998035944-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | BAYER CORPORATION (US) | 1998-08-20 | — | — | WO | claimed |
| EP-0415294-A2 | Cyclohexanol derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1991-03-06 | — | — | EP | claimed |
| CN-108368107-B | Fused heterocyclic compounds as S1P modulators | 艾伯维公司 | 2021-11-26 | — | — | CN | disclosed |
| US-20200055817-A1 | SPIRO-COMPOUNDS AS SIP MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-20 | — | — | US | disclosed |
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
| EP-3535244-A1 | SPIRO-COMPOUNDS AS S1P MODULATORS | Abbvie Deutschland GmbH & Co. KG (DE) | 2019-09-11 | — | — | EP | disclosed |
| US-10280159-B2 | Fused (hetero)cyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2019-05-07 | — | — | US | disclosed |
| EP-2670733-B1 | N-HYDROXYBENZAMIDE DERIVATIVES AS HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV ILLINOIS (US) | 2019-04-10 | — | — | EP | disclosed |
| EP-3394050-A1 | FUSED (HETERO)CYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-10-31 | — | — | EP | disclosed |
| EP-3341369-A1 | FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS | AbbVie Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20130184272-A1 | DIABETES THERAPEUTIC AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-18 | — | — | US | disclosed |
| EP-0927166-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | Bayer Corporation (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998035944-A1 | AMIDES AS NPY5 RECEPTOR ANTAGONISTS | BAYER CORPORATION (US) | 1998-08-20 | — | — | WO | disclosed |
| EP-0822936-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO 3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996033999-A1 | NOVEL SUBSTITUTED TETRAHYDROPYRANO[3,2-d]OXAZOLONES, METHOD FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1996-10-31 | — | — | WO | disclosed |
| US-4997985-A | Alpha amino acid amide compounds which are useful intermediates in the preparation of herbicides | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4895588-A | Substituted imidazolones having herbicidal activity | CIBA-GEIGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4219648-A | 7-[[Amino(1,3-dihydrobenzo[c]thienyl)acetyl]amino]cephalosporin derivatives | RICHARDSON-MERRELL INC. (US) | 1980-08-26 | — | — | US | disclosed |