Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | THPO | P40225 | 1/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 7/20 | 0.64 |
| ▸ | CACNA1D | Q01668 | 7/20 | 0.64 |
| ▸ | CACNA1S | Q13698 | 7/20 | 0.64 |
| ▸ | CACNA1C | Q13936 | 7/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329073 | 0.97 | CACNA1F (0.66) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7442951 | 0.92 | CACNA1F (0.75) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL10429056 | 0.91 | HIF1A (0.78) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7365827 | 0.91 | CACNA1F (0.75) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL3435282 | 0.89 | CACNA1F (0.78) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL10686194 | 0.88 | CACNA1F (0.79) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7343596 | 0.86 | MAPT (0.60) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL9008600 | 0.86 | MAPT (0.55) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7281098 | 0.86 | HIF1A (0.81) | HIF1AMEN1KMT2AMAPTCYP1A2 | |
| SCHEMBL7427122 | 0.86 | CACNA1F (0.80) | HIF1AMEN1KMT2AMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0552379-B1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-10-30 | — | — | EP | disclosed |
| EP-0552379-A1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION. | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-07-28 | — | — | EP | disclosed |
| WO-1993003014-A1 | DIHYDROPYRIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |