Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327447 | 1.00 | CA14 (0.48) | CA14SMN1; SMN2MAPTL3MBTL1KDM1A | |
| SCHEMBL10421860 | 0.89 | CA14 (0.56) | CA14SMN1; SMN2MAPTL3MBTL1KDM1A | |
| SCHEMBL4572684 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL4572680 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL109878 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL2807366 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL3808901 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL88208 | 0.84 | TP53 (0.47) | TP53MMEFOLH1 | |
| SCHEMBL10882828 | 0.79 | MGAM (0.41) | MME | |
| SCHEMBL10970199 | 0.79 | MGAM (0.41) | MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472380-A | CARBOXYALKYL DIPEPTIDE DERIVATIVES | MERCK & CO., INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4374829-A | Aminoacid derivatives as antihypertensives | MERCK & CO., INC. (US) | 1983-02-22 | — | — | US | disclosed |