⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4421197 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL2122714 | 0.97 | — | — | |
| SCHEMBL4533538 | 0.83 | — | — | |
| SCHEMBL9211224 | 0.79 | TSHR (0.48) | — | |
| SCHEMBL9211258 | 0.79 | TSHR (0.48) | — | |
| SCHEMBL4306492 | 0.78 | — | — | |
| SCHEMBL23192221 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL11561461 | 0.76 | — | — | |
| SCHEMBL1903966 | 0.76 | TSHR (0.33) | — | |
| SCHEMBL73805 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108623898-A | The spacer bar of antimildew and antibacterial polypropylene material and preparation method with the application material | 石家庄欧强节能建材科技有限公司 | 2018-10-09 | — | — | CN | claimed |
| EP-2236502-B1 | SULFENAMIDE, VULCANIZATION ACCELERATOR CONTAINING THE SULFENAMIDE FOR RUBBER, AND PROCESS FOR PRODUCING THE VULCANIZATION ACCELERATOR | OUCHI SHINKO CHEMICAL IND CO LTD (JP) | 2014-03-05 | — | — | EP | claimed |
| US-20250340568-A1 | SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION | VERTEX PHARMA (US) | 2025-11-06 | — | — | US | disclosed |
| US-12324802-B2 | Modulators of cystic fibrosis transmembrane conductance regulator | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-06-10 | — | — | US | disclosed |
| CN-119731183-A | Solid forms of macrocyclic compounds as CFTR modulators and their preparation | 弗特克斯药品有限公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-4525858-A1 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | Vertex Pharmaceuticals Incorporated (US) | 2025-03-26 | — | — | EP | disclosed |
| EP-4525986-A1 | SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION | Vertex Pharmaceuticals Incorporated (US) | 2025-03-26 | — | — | EP | disclosed |
| WO-2023224924-A1 | SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023224924-A1 | SOLID FORMS OF A MACROCYCLIC COMPOUNDS AS CFTR MODULATORS AND THEIR PREPARATION | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023224931-A1 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023224931-A1 | METHODS OF TREATMENT FOR CYSTIC FIBROSIS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-11-23 | — | — | WO | disclosed |
| US-7879797-B2 | HCV NS3 protease inhibitors | MERCK SHARP & DOHME CORP. (US) | 2011-02-01 | — | — | US | disclosed |
| US-20100317623-A1 | HCV NS3 Protease Inhibitors | MERCK SHARP & DOHME LLC | 2010-12-16 | — | — | US | disclosed |
| WO-2010079467-A2 | DELIVERY PARTICLES | THE PROCTER & GAMBLE COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| EP-2079479-A2 | HCV NS3 PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008051475-A2 | HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| EP-1913016-A1 | MACROCYCLIC PEPTIDES AS HCV NS3 PROTEASE INHIBITORS | Merck & Co., Inc. (US) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007016441-A1 | MACROCYCLIC PEPTIDES AS HCV NS3 PROTEASE INHIBITORS | MERCK & CO., INC. (US) | 2007-02-08 | — | — | WO | disclosed |
| EP-1223161-A2 | Method to stabilise and/or lower the color number of alkenyl compounds | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-17 | — | — | EP | disclosed |
| EP-0438385-A1 | Procedure and additive for preventing clogging of a handling process of dry cellulose-containing material | OY ALKO AB (FI) | 1991-07-24 | — | — | EP | disclosed |