Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.63 |
| ▸ | PDE4B | Q07343 | 18/20 | 0.63 |
| ▸ | PDE4C | Q08493 | 18/20 | 0.63 |
| ▸ | PDE4D | Q08499 | 18/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331457 | 1.00 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8574868 | 1.00 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7328122 | 1.00 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7328726 | 1.00 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8573925 | 1.00 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7335922 | 0.92 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7787744 | 0.92 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7335920 | 0.92 | PDE4A (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7795024 | 0.89 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7417063 | 0.89 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722322-A4 | COMPOUNDS, COMPOSITIONS AND TREATMENT OF ALLERGIES AND INFLAMMATION THEREWITH | SMITHKLINE BEECHAM CORP (US) | 1999-03-10 | — | — | EP | claimed |
| EP-0722322-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENT OF ALLERGIES AND INFLAMMATION THEREWITH | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-24 | — | — | EP | claimed |
| WO-1995009627-A1 | COMPOUNDS, COMPOSITIONS AND TREATMENT OF ALLERGIES AND INFLAMMATION THEREWITH | SMITHKLINE BEECHAM CORPORATION (US) | 1995-04-13 | — | — | WO | claimed |