Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 18/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262127 | 0.84 | CYP1B1 (0.67) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL26243132 | 0.84 | CYP1B1 (0.70) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL28094481 | 0.82 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL29493708 | 0.82 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL10261817 | 0.82 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL20419197 | 0.82 | CYP1B1 (0.78) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL29697183 | 0.82 | CYP1B1 (0.78) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL30353799 | 0.82 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL28781801 | 0.82 | CYP1B1 (0.68) | CYP1B1ALDH1A1POLBRXFP1KDM4E | |
| SCHEMBL10261574 | 0.82 | CYP1B1 (0.77) | CYP1B1ALDH1A1POLBRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181255-A | Microenvironment polarity activated mitochondrial targeting probe and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-03-15 | — | — | CN | claimed |
| CN-114181255-A | Microenvironment polarity activated mitochondrial targeting probe and application thereof | 山东第一医科大学(山东省医学科学院) | 2022-03-15 | — | — | CN | disclosed |
| CN-108276442-B | Mitochondrial targeting formaldehyde fluorescent probe and preparation method and application thereof | 济南大学 | 2020-07-07 | — | — | CN | disclosed |
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |
| WO-1993009136-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1993-05-13 | — | — | WO | disclosed |