Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300746 | 0.77 | — | — | |
| SCHEMBL27816064 | 0.72 | SLC18A3 (0.41) | SLC18A3 | |
| SCHEMBL5398154 | 0.72 | SLC18A3 (0.41) | SLC18A3 | |
| SCHEMBL19468663 | 0.68 | — | — | |
| SCHEMBL6519582 | 0.63 | SLC18A3 (0.38) | SLC18A3 | |
| SCHEMBL1404005 | 0.63 | SLC18A3 (0.38) | SLC18A3 | |
| SCHEMBL20399990 | 0.61 | MAN2B1 (0.39) | SLC18A3 | |
| SCHEMBL1404038 | 0.59 | SLC18A3 (0.44) | SLC18A3 | |
| SCHEMBL1648569 | 0.58 | — | — | |
| SCHEMBL2801018 | 0.58 | SLC18A3 (0.38) | SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194605-A | Treatment of hypertension, hyperaldosteronism, congestive heart failure, glaucoma | MERCK & CO., INC. (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0518676-A2 | Cyclic renin inhibitors | MERCK & CO. INC. (US) | 1992-12-16 | — | — | EP | disclosed |
| EP-0432975-A1 | Cyclic renin inhibitors | MERCK & CO. INC. (US) | 1991-06-19 | — | — | EP | disclosed |