Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.43 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15987696 | 0.88 | ESR1 (0.54) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL713812 | 0.83 | ESR2 (0.63) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL694397 | 0.83 | MAPK1 (0.65) | HCAR1HTTMAPK1ALDH1A1TSHR | |
| SCHEMBL715626 | 0.83 | ESR2 (0.68) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL15987336 | 0.82 | ESR1 (0.58) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL27987926 | 0.82 | ESR2 (0.58) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL21382719 | 0.81 | ESR1 (0.58) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL541157 | 0.80 | ESR2 (0.78) | ESR1ESR2HCAR1GRIA1CACNG8 | |
| SCHEMBL731625 | 0.79 | ATM (0.56) | HTTMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL30282233 | 0.78 | ESR2 (0.76) | ESR1ESR2HCAR1GRIA1CACNG8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240122065-A1 | METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN | TOSOH CORPORATION (JP) | 2024-04-11 | — | — | US | disclosed |
| EP-4342883-A1 | PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT | Tosoh Corporation (JP) | 2024-03-27 | — | — | EP | disclosed |
| CN-117440940-A | Material for photoelectric conversion element for image pickup element and photoelectric conversion element for image pickup element | 东曹株式会社 | 2024-01-23 | — | — | CN | disclosed |
| CN-110997648-B | Condensed ring compound | 东曹株式会社 | 2023-12-19 | — | — | CN | disclosed |
| CN-117044428-A | Lateral current suppressing material, carbazole compound, hole injection layer, and organic electroluminescent element | 东曹株式会社 | 2023-11-10 | — | — | CN | disclosed |
| EP-4198163-A1 | METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN | Tosoh Corporation (JP) | 2023-06-21 | — | — | EP | disclosed |
| CN-116157382-A | Material for metal patterning, amine compound, electronic device, and method for forming metal pattern | 东曹株式会社 | 2023-05-23 | — | — | CN | disclosed |
| WO-2023013615-A1 | AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2023-02-09 | — | — | WO | disclosed |
| WO-2023013697-A1 | MATERIAL FOR METAL PATTERNING, FLUORO COMPOUND, THIN FILM FOR METAL PATTERNING, ORGANIC ELECTROLUMINESCENCE DEVICE, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN | 東ソー株式会社 | 2023-02-09 | — | — | WO | disclosed |
| WO-2022260096-A1 | PHOTOELECTRIC CONVERSION ELEMENT MATERIAL FOR IMAGING ELEMENT AND PHOTOELECTRIC CONVERSION ELEMENT FOR IMAGING ELEMENT | 東ソー株式会社 | 2022-12-15 | — | — | WO | disclosed |
| EP-2772483-B1 | 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME | TOSOH CORP (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-9172045-B2 | 4-aminocarbazole compound and use thereof | TOSOH CORPORATION (JP) | 2015-10-27 | — | — | US | disclosed |
| US-20140296519-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2772483-A1 | 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME | Tosoh Corporation (JP) | 2014-09-03 | — | — | EP | disclosed |
| CN-104011022-A | 4-aminocarbazole compound and use of same | TOSOH CORP | 2014-08-27 | — | — | CN | disclosed |
| EP-2120569-B1 | SPIROCHROMANON DERIVATIVES | MERCK SHARP & DOHME (US) | 2013-08-14 | — | — | EP | disclosed |
| US-8138197-B2 | Spirochromanon derivatives | MSD K.K. (JP) | 2012-03-20 | — | — | US | disclosed |
| EP-2120569-A2 | SPIROCHROMANON DERIVATIVES | Merck & Co., Inc. (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20090270436-A1 | SPIROCHROMANON DERIVATIVES | MERCK SHARP & DOHME LLC | 2009-10-29 | — | — | US | disclosed |
| WO-2008088692-A2 | SPIROCHROMANON DERIVATIVES | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270436-A1 | SPIROCHROMANON DERIVATIVES | AKR1C3, CBR3, AKR1C4 | ESR1 1044/4885ESR2 708/4885HCAR1 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.