Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653605 | 1.00 | KDM1A (0.44) | KDM1ABCHEMEN1KMT2AKDM4C | |
| Hydrochloric Acid SCHEMBL8652265 | 0.99 | KDM1A (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| SCHEMBL7326833 | 0.88 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| SCHEMBL7328323 | 0.88 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| Hydrochloric Acid SCHEMBL8654015 | 0.87 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| Hydrochloric Acid SCHEMBL7336284 | 0.87 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| Hydrochloric Acid SCHEMBL7358403 | 0.87 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| Hydrochloric Acid SCHEMBL7359935 | 0.87 | BCHE (0.43) | KDM1ABCHEMEN1KMT2AKDM4C | |
| SCHEMBL8650717 | 0.80 | NPC1 (0.41) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL7337139 | 0.80 | NPC1 (0.41) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | claimed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | claimed |
| EP-0711271-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004027-A1 | AMINOINDANES AND RELATED COMPOUNDS USEFUL AS CALCIUM-CHANNEL ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |