Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.57 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329314 | 1.00 | KDM1A (0.57) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL5341308 | 1.00 | KDM1A (0.57) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL5704636 | 1.00 | KDM1A (0.57) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL14284253 | 1.00 | KDM1A (0.57) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| Hydrochloric Acid SCHEMBL11695201 | 0.98 | KDM1A (0.59) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL5070767 | 0.83 | KDM1A (0.48) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL30608698 | 0.78 | KDM1A (0.39) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL18544377 | 0.74 | CHRNB4 (0.43) | KDM1AKDM1BMAOBMAOAHTR2C | |
| SCHEMBL7094448 | 0.73 | HTR2C (0.58) | KDM1AKDM1BMAOBMAOACYP2C19 | |
| SCHEMBL7864324 | 0.73 | HTR2C (0.58) | KDM1AKDM1BMAOBMAOACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089506-A | Antipsychotic agents, anticonvulsants | G. D. SEARLE & CO. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0455195-A2 | Ethanobicyclic amine derivatives for CNS disorders | G.D. Searle & Co. (US) | 1991-11-06 | — | — | EP | disclosed |