SCHEMBL7329413

SCHEMBL7329413

COCCCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 5/20 0.77
TP53 P04637 1/20 0.69
TSHR P16473 1/20 0.69
PLA2G4B P0C869 7/20 0.67
HTT P42858 2/20 0.63
PLA2G4A P47712 1/20 0.60
POLB P06746 1/20 0.58
APEX1 P27695 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
PKM P14618 1/20 0.57
GAA P10253 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7340390 1.00 RARB (0.77) RARBTP53TSHRPLA2G4BHTT
SCHEMBL7332700 1.00 RARB (0.77) RARBTP53TSHRPLA2G4BHTT
SCHEMBL18682414 1.00 RARB (0.77) RARBTP53TSHRPLA2G4BHTT
SCHEMBL8747416 0.98 RARB (0.74) RARBTP53TSHRPLA2G4BHTT
SCHEMBL18682480 0.95 TP53 (0.75) RARBTP53TSHRPLA2G4BHTT
SCHEMBL6132656 0.95 TP53 (0.75) RARBTP53TSHRPLA2G4BHTT
SCHEMBL6132822 0.95 TP53 (0.75) RARBTP53TSHRPLA2G4BHTT
SCHEMBL13861910 0.90 RARB (0.68) RARBTP53TSHRPLA2G4BHTT
SCHEMBL2882011 0.90 PLA2G4B (0.70) RARBTP53TSHRPLA2G4BHTT
SCHEMBL7323524 0.88 NR1H4 (0.64) RARBTP53TSHRPLA2G4BHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1203089-C New compound FUJISAWA PHARMACEUTICAL CO (JP) 2005-05-25 CN disclosed
EP-0788511-B1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO (JP) 2002-12-11 EP disclosed
US-6265536-B1 MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-07-24 US disclosed
US-6107458-A FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2000-08-22 US disclosed
CN-1168675-A Novel compounds FUJISAWA PHARMACEUTICAL CO (JP) 1997-12-24 CN disclosed
EP-0788511-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1997-08-13 EP disclosed
WO-1996011210-A1 CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-04-18 WO disclosed