⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199341 | 0.68 | — | — | |
| SCHEMBL28161986 | 0.65 | — | — | |
| SCHEMBL11376137 | 0.64 | — | — | |
| SCHEMBL11386773 | 0.64 | — | — | |
| SCHEMBL11379603 | 0.62 | — | — | |
| SCHEMBL27627179 | 0.58 | — | — | |
| SCHEMBL11146882 | 0.58 | — | — | |
| SCHEMBL11147085 | 0.58 | — | — | |
| SCHEMBL11194425 | 0.57 | — | — | |
| SCHEMBL11198813 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083987-A | 4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat and immuno-stimulant | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-11 | — | — | US | claimed |
| US-4517183-A | COMBATING DISEASES WITH WEAKNESS OF IMMUNE SYSTEMS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-05-14 | — | — | US | disclosed |
| US-4397848-A | ANTITUMOR ACTIVITY | BOEHRINGER MANNHEIM GMBH (DE) | 1983-08-09 | — | — | US | disclosed |
| US-4370323-A | 2-Cyanoaziridinyl-(1)-2-substituted-aziridinyl-(1)-methanes | BOEHRINGER MANNHEIM GMBH (DE) | 1983-01-25 | — | — | US | disclosed |
| US-4282212-A | Immune-stimulating 1-(N-acylcarbamoyl)-2-cyanoaziridines | BOEHRINGER MANNHEIM GMBH (DE) | 1981-08-04 | — | — | US | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |
| EP-0014976-A1 | N-substituted 2-cyanaziridines, methods for their preparation and medicaments containing them, correspondingly substituted aziridine-2-carbonamides and their preparation | Roche Diagnostics GmbH (DE) | 1980-09-03 | — | — | EP | disclosed |
| US-4083987-A | 4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat and immuno-stimulant | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-11 | — | — | US | disclosed |
| US-4083987-A | 4-Imino-1,3-diazabicyclo-(3.1.0)-hexan-2-one as a cancerostat and immuno-stimulant | BOEHRINGER MANNHEIM GMBH (DT) | 1978-04-11 | — | — | US | disclosed |