Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841439 | 0.86 | TDP1 (0.50) | TDP1L3MBTL1 | |
| SCHEMBL586406 | 0.86 | TDP1 (0.50) | TDP1L3MBTL1 | |
| SCHEMBL4168183 | 0.86 | TDP1 (0.50) | TDP1L3MBTL1 | |
| SCHEMBL29373976 | 0.86 | TDP1 (0.50) | TDP1L3MBTL1 | |
| SCHEMBL13771640 | 0.85 | TDP1 (0.49) | TDP1L3MBTL1 | |
| SCHEMBL17019828 | 0.85 | — | — | |
| SCHEMBL1566425 | 0.81 | BCHE (0.45) | TDP1L3MBTL1 | |
| SCHEMBL2815497 | 0.80 | TSHR (0.51) | — | |
| SCHEMBL5002484 | 0.80 | BCHE (0.45) | — | |
| SCHEMBL11162597 | 0.80 | ELANE (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598071-A | ANGIOTENSIN INHIBITORS/ | E. R. SQUIBB & SONS, INC. (US) | 1986-07-01 | — | — | US | disclosed |
| US-4567167-A | INHIBITOR OF ANGIOTENDIN CONVERTING ENZYME | E. R. SQUIBB & SONS, INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4533661-A | Certain 3-phosphinyl-amino-2-oxo-1H-azepine-1-acetic acid derivatives having anti-hypertensive activity | E. R. SQUIBB & SONS, INC. (US) | 1985-08-06 | — | — | US | disclosed |