Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.35 |
| ▸ | PDE4A | P27815 | 7/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326213 | 1.00 | SERPINE1 (0.37) | SERPINE1EPHX1ALDH1A1HPGDEPHX2 | |
| SCHEMBL7325124 | 0.91 | TRPV1 (0.40) | SERPINE1EPHX1ALDH1A1HPGDMAPT | |
| SCHEMBL7327388 | 0.91 | TRPV1 (0.40) | SERPINE1EPHX1ALDH1A1HPGDMAPT | |
| SCHEMBL7324386 | 0.85 | SERPINE1 (0.40) | SERPINE1EPHX1EPHX2PDE4BPDE4A | |
| SCHEMBL7320525 | 0.83 | SERPINE1 (0.42) | SERPINE1EPHX1TRPV1PDE4BPDE4A | |
| SCHEMBL7326208 | 0.81 | PDE4A (0.38) | SERPINE1EPHX1ALDH1A1HPGDEPHX2 | |
| SCHEMBL7329509 | 0.81 | PDE4A (0.38) | SERPINE1EPHX1ALDH1A1HPGDEPHX2 | |
| SCHEMBL7322794 | 0.80 | PDE4B (0.45) | EPHX1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7322847 | 0.80 | PDE4B (0.45) | EPHX1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7328147 | 0.77 | SERPINE1 (0.39) | SERPINE1EPHX1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0557408-A4 | IMIDAZOLIDINONE COMPOUNDS | — | 1993-10-27 | — | — | EP | disclosed |
| EP-0557408-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-09-01 | — | — | EP | disclosed |
| WO-1992007567-A1 | IMIDAZOLIDINONE COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-05-14 | — | — | WO | disclosed |