Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739521 | 0.84 | HPGD (0.62) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL30898290 | 0.80 | TSHR (0.57) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL29212238 | 0.80 | TSHR (0.57) | GRIA1GRIA2GRIA3GRIA4HPGD | |
| SCHEMBL25275996 | 0.78 | HPGD (0.56) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL25275997 | 0.78 | HPGD (0.56) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL23997240 | 0.78 | HPGD (0.56) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL23997410 | 0.78 | HPGD (0.56) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL25279330 | 0.78 | HPGD (0.56) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL7248358 | 0.77 | HPGD (0.74) | HPGDOPRM1OPRK1OPRL1MEN1 | |
| SCHEMBL982104 | 0.77 | CYP1A2 (0.69) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |