Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 15/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329296 | 1.00 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7329294 | 1.00 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336154 | 0.94 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336378 | 0.94 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336375 | 0.94 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336370 | 0.94 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7329446 | 0.94 | VIPR2 (0.48) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336101 | 0.93 | VIPR2 (0.47) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7333668 | 0.92 | VIPR2 (0.49) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7333662 | 0.92 | VIPR2 (0.49) | VIPR2MMP9MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | claimed |
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |