Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.47 |
| ▸ | KISS1R | Q969F8 | 7/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7330286 | 1.00 | BACE1 (0.47) | BACE1KISS1RCTSD | |
| SCHEMBL31433283 | 0.84 | NAALAD2 (0.52) | BACE1CTSD | |
| SCHEMBL31366242 | 0.83 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL30272495 | 0.82 | GNPAT (0.53) | BACE1 | |
| SCHEMBL10741034 | 0.82 | FCER2 (0.50) | KISS1R | |
| SCHEMBL10741046 | 0.82 | FCER2 (0.50) | KISS1R | |
| SCHEMBL31276975 | 0.82 | MME (0.53) | BACE1CTSD | |
| SCHEMBL30460370 | 0.81 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL29590787 | 0.81 | BACE1 (0.60) | BACE1CTSD | |
| SCHEMBL30979971 | 0.81 | NAALAD2 (0.53) | BACE1KISS1RCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | claimed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |