Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8760 | 0.85 | KMT2A (0.67) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL146434 | 0.83 | KMT2A (0.65) | KMT2AMMEMEN1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL23235729 | 0.83 | KMT2A (0.65) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL9062437 | 0.83 | KMT2A (0.65) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL10405578 | 0.83 | KMT2A (0.65) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL2236118 | 0.81 | KMT2A (0.63) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL1790978 | 0.81 | KMT2A (0.63) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL21538610 | 0.81 | KMT2A (0.63) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL21538582 | 0.81 | KMT2A (0.63) | KMT2AMMEMEN1ALDH1A1MAPT | |
| SCHEMBL5023170 | 0.81 | KMT2A (0.73) | KMT2AMMEMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474783-A | CARDIAC DISEASES SYMPTOMIZED BY LOW CARIAC FLOW | INNOTHERA (FR) | 1984-10-02 | — | — | US | disclosed |