Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HTR2B | P41595 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.68 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7409497 | 1.00 | MAPT (0.68) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL10943776 | 1.00 | MAPT (0.68) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL7409852 | 1.00 | MAPT (0.68) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL22157909 | 0.89 | MAPT (0.69) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL17165949 | 0.87 | MAPT (0.66) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL4398494 | 0.85 | MAPT (0.53) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15344010 | 0.84 | MAPT (0.73) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL15695725 | 0.82 | MAPT (0.70) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL22172489 | 0.82 | MAPT (0.59) | MAPTTDP1LMNAPGRCYP3A4 | |
| SCHEMBL25968998 | 0.82 | MAPT (0.59) | MAPTTDP1LMNAPGRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563129-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-08 | — | — | US | disclosed |
| US-5534639-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-09 | — | — | US | disclosed |
| US-5436359-A | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0560568-A2 | Hydroquinone derivatives and intermediates for production thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-15 | — | — | EP | disclosed |
| US-4831265-A | ANTIFIBROTIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| US-4559177-A | HYPOTENSIVE, CARDIOTONIC AND ANTIPHYLATIC AGENTS; ANTIALLERGENS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-12-17 | — | — | US | disclosed |
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4514420-A | Antifibrotic agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0021841-B1 | 2,3-DIALKOXY-1,4-QUINONE DERIVATIVES; METHOD OF PRODUCING 1,4-QUINONE DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| EP-0058057-A1 | Method of producing quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1982-08-18 | — | — | EP | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| EP-0021841-A2 | 2,3-Dialkoxy-1,4-quinone derivatives; method of producing 1,4-quinone derivatives | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |