Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.67 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338724 | 0.89 | ELANE (0.70) | ELANECTRB1 | |
| SCHEMBL7330024 | 0.87 | ELANE (0.67) | ELANECTRB1KDM4ENPC1RAB9A | |
| SCHEMBL7338605 | 0.82 | ELANE (0.70) | ELANECTRB1 | |
| SCHEMBL6498064 | 0.81 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL6499857 | 0.80 | ELANE (0.74) | ELANECTRB1KDM4ENPC1RAB9A | |
| SCHEMBL10362711 | 0.72 | ELANE (1.00) | ELANECTRB1 | |
| SCHEMBL6503868 | 0.71 | ELANE (0.71) | ELANECTRB1 | |
| SCHEMBL6501226 | 0.71 | ELANE (0.67) | ELANECTRB1 | |
| SCHEMBL8898683 | 0.69 | C1R (0.73) | ELANECTRB1 | |
| SCHEMBL6504112 | 0.69 | ELANE (1.00) | ELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996007648-A1 | 2-SUBSTITUTED-4H-3,1-BENZOXAZIN-4-ONES AND BENZTHIAZIN-4-ONES AS INHIBITORS OF COMPLEMENT Clr PROTEASE FOR THE TREATMENT OF INFLAMMATORY PROCESSES | WARNER-LAMBERT COMPANY (US) | 1996-03-14 | — | — | WO | disclosed |