Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.68 |
| ▸ | CA1 | P00915 | 2/20 | 0.68 |
| ▸ | CA2 | P00918 | 2/20 | 0.68 |
| ▸ | CA9 | Q16790 | 2/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.64 |
| ▸ | THRA | P10827 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 3/20 | 0.62 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093620 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL11349336 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL15094111 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL15093871 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL11352018 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL11353893 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL15093429 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL27905675 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL11361435 | 0.90 | CA12 (0.76) | CA12CA1CA2CA9S1PR1 | |
| SCHEMBL15093703 | 0.89 | CA12 (0.73) | CA12CA1CA2CA9S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-B1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6265536-B1 | MICROBIOCIDE AND FUNGICIDE WHICH IS INHIBITOR OF BETA-1,3-GLUCAN SYNTHASE; TREATMENT OF PNEUMOCYSTIS CARINII INFECTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996011210-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-18 | — | — | WO | disclosed |