Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 12/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 10/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.65 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334239 | 1.00 | PDE4B (0.65) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| SCHEMBL7334711 | 0.85 | PDE4B (0.61) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| SCHEMBL7333823 | 0.85 | PDE4B (0.71) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| SCHEMBL7355649 | 0.83 | PDE4B (0.82) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| SCHEMBL7364522 | 0.80 | PDE4B (0.67) | PDE4BPDE4DPDE4APDE4CPDE3B | |
| Filaminast SCHEMBL73843 | 0.79 | PDE4D (1.00) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL13986144 | 0.79 | PDE4D (1.00) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL73844 | 0.79 | PDE4D (1.00) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| Filaminast SCHEMBL29412441 | 0.79 | PDE4D (1.00) | PDE4BPDE4DMAPK14PDE4APDE4C | |
| SCHEMBL5030807 | 0.79 | PDE4B (0.63) | PDE4BPDE4DPDE4APDE4CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470805-B1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PROD (US) | 1994-09-07 | — | — | EP | claimed |
| EP-0470805-A1 | Oxime-carbamates and oxime-carbonates as bronchodilators and anti-inflammatory agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-02-12 | — | — | EP | claimed |