Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VIPR2 | P41587 | 16/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334376 | 1.00 | VIPR2 (0.53) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7300421 | 0.90 | VIPR2 (0.58) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7300433 | 0.90 | VIPR2 (0.58) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7329273 | 0.90 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336375 | 0.90 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336378 | 0.90 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336370 | 0.90 | VIPR2 (0.52) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336151 | 0.89 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336157 | 0.89 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 | |
| SCHEMBL7336153 | 0.89 | VIPR2 (0.51) | VIPR2MMP9MMP1MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434365-A2 | HIV protease inhibitors useful for the treatment of aids | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |