Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 20/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 20/20 | 0.81 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.73 |
| ▸ | PDE2A | O00408 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334616 | 0.90 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7334731 | 0.88 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7335008 | 0.86 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7327142 | 0.86 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL10657958 | 0.84 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL9852356 | 0.84 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7335021 | 0.83 | PDE3B (0.77) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL7334081 | 0.82 | PDE3B (1.00) | PDE3BPDE3AP2RY12 | |
| SCHEMBL6571766 | 0.82 | PDE3B (1.00) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7323900 | 0.81 | PDE3B (1.00) | PDE3BPDE3AP2RY12PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4943573-A | ENZYME INHIBITORS, CARDIOTONIC, ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-07-24 | — | — | US | claimed |