SCHEMBL7335221

SCHEMBL7335221

C[C@@H](C(=O)O)[C@H](N)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.63
SLC1A3 P43003 3/20 0.46
SLC1A2 P43004 3/20 0.46
SLC1A1 P43005 2/20 0.46
TP53 P04637 1/20 0.42
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
GABRP O00591 4/20 0.36
GABRD O14764 4/20 0.36
GABRA1 P14867 4/20 0.36
GABRB1 P18505 4/20 0.36
GABRG2 P18507 4/20 0.36
GABRB3 P28472 4/20 0.36
GABRA5 P31644 4/20 0.36
GABRA3 P34903 4/20 0.36
GABRA2 P47869 4/20 0.36
GABRB2 P47870 4/20 0.36
GABRA4 P48169 4/20 0.36
GABRE P78334 4/20 0.36
GABRA6 Q16445 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2266575 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
SCHEMBL2895827 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
SCHEMBL83870 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
SCHEMBL9135178 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
SCHEMBL4330500 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
SCHEMBL87358 1.00 SLC7A5 (0.63) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Hydrochloric Acid SCHEMBL7920996 0.97 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Hydrochloric Acid SCHEMBL7920991 0.97 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Hydrochloric Acid SCHEMBL9132421 0.97 SLC7A5 (0.60) SLC7A5SLC1A3SLC1A2SLC1A1TP53
Sulfuric Acid SCHEMBL9403169 0.89 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4508235-A2 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL University of Utah Research Foundation (US) 2025-02-19 EP disclosed
WO-2023201372-A2 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2023-10-19 WO disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
EP-0827507-B1 PROTEASE INHIBITING SUCCINIC ACID DERIVATIVES BOEHRINGER INGELHEIM CA LTD (CA) 1999-06-16 EP disclosed
US-5846941-A Isosteric antiherpes peptide derivatives II BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1998-12-08 US disclosed
EP-0560267-B1 Isosteric antiherpes peptide derivatives BOEHRINGER INGELHEIM CA LTD (CA) 1998-08-19 EP disclosed
EP-0560274-B1 Antiherpes peptide derivatives having a ureido N-terminus BOEHRINGER INGELHEIM CA LTD (CA) 1998-06-24 EP disclosed
US-5574015-A Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1996-11-12 US disclosed
US-5545640-A VIRICIDES, HIV; AIDS BIO-MEGA/BOEHRINGER INGELEHEIM RESEARCH INC. (CA) 1996-08-13 US disclosed
CN-1118601-A Inhibitors of herpes viral ribonucleotide reductase BIO MEGA BOEHRINGER INGELHEIM (CA) 1996-03-13 CN disclosed
US-5476841-A Inhibitors of herpes viral ribonucleotide reductase BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1995-12-19 US disclosed
CN-1096300-A Isosteric antiherpes peptide derivatives BIO MEGA BOEHRINGER INGELHEIM (CA) 1994-12-14 CN disclosed
EP-0618226-A1 Inhibitors of herpes viral ribonculeotide reductase BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-10-05 EP disclosed
WO-1994020528-A1 INHIBITORS OF HERPES VIRAL RIBONUCLEOTIDE REDUCTASE BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1994-09-15 WO disclosed
WO-1993018056-A1 ISOSTERIC ANTIHERPES PEPTIDE DERIVATIVES BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-16 WO disclosed
EP-0560274-A1 Antiherpes peptide derivatives having a ureido N-terminus BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed
EP-0560267-A1 Isosteric antiherpes peptide derivatives BIO-MEGA/BOEHRINGER INGELHEIM RESEARCH INC. (CA) 1993-09-15 EP disclosed
US-4981794-A BIOSYNTHESIS E. R. SQUIBB & SONS, INC. (US) 1991-01-01 US disclosed
US-4310635-A Fermentative production of D(-)-β-hydroxyisobutyric acid KANEGAFUCHI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-01-12 US disclosed