Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 3/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7342153 | 0.99 | AVPR2 (0.38) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| SCHEMBL7345296 | 0.93 | AVPR2 (0.39) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| Hydrochloric Acid SCHEMBL7338873 | 0.93 | POLB (0.42) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| SCHEMBL7338872 | 0.92 | POLB (0.43) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| Hydrochloric Acid SCHEMBL7335616 | 0.91 | POLB (0.42) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| SCHEMBL7340626 | 0.91 | POLB (0.39) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| Hydrochloric Acid SCHEMBL8010882 | 0.90 | POLB (0.35) | AVPR2AVPR1ANAMPTPOLBKMT2A | |
| SCHEMBL7344522 | 0.89 | KMT2A (0.41) | AVPR2AVPR1AAVPR1BSMN1; SMN2KMT2A | |
| SCHEMBL7347838 | 0.89 | POLB (0.44) | AVPR2AVPR1ANAMPTAVPR1BPOLB | |
| Hydrochloric Acid SCHEMBL7346264 | 0.88 | POLB (0.43) | AVPR2AVPR1ANAMPTAVPR1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |