Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 17/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7339437 | 0.91 | TP53 (0.44) | AVPR2AVPR1ATP53SHMT2 | |
| SCHEMBL7342384 | 0.89 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL7339456 | 0.88 | AVPR2 (0.56) | AVPR2AVPR1ATP53 | |
| SCHEMBL7343152 | 0.87 | AVPR2 (0.54) | AVPR2AVPR1ATP53 | |
| SCHEMBL7341306 | 0.86 | AVPR2 (0.51) | AVPR2AVPR1ATP53 | |
| SCHEMBL7339425 | 0.86 | AVPR2 (0.48) | AVPR2AVPR1ATP53SHMT2 | |
| SCHEMBL7343351 | 0.83 | AVPR2 (0.61) | AVPR2AVPR1ATP53SHMT2 | |
| SCHEMBL7334113 | 0.80 | AVPR2 (0.54) | AVPR2AVPR1ATP53SHMT2 | |
| SCHEMBL7342906 | 0.79 | AVPR2 (0.49) | AVPR2AVPR1ATP53SHMT2 | |
| SCHEMBL7343689 | 0.79 | AVPR2 (0.48) | AVPR2AVPR1ATP53SHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |