Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2637743 | 0.83 | HPGD (0.61) | KDM4EHPGDALOX15CYP1A2CYP2C9 | |
| SCHEMBL73570 | 0.82 | KDM4E (0.54) | KDM4EHPGDALOX15CYP1A2CYP2C9 | |
| SCHEMBL22550480 | 0.81 | SMN1; SMN2 (0.56) | KDM4EALOX15ARSMN1; SMN2HTT | |
| SCHEMBL75565 | 0.81 | KDM4E (0.51) | KDM4EHPGDALOX15ARCYP1A2 | |
| SCHEMBL16303150 | 0.80 | AR (0.52) | KDM4EARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20718423 | 0.79 | AR (0.47) | ALOX15ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20718208 | 0.79 | AR (0.47) | ALOX15ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL20718419 | 0.79 | AR (0.47) | ALOX15ARSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2596875 | 0.79 | AR (0.56) | ARSMARCA2SMARCA4 | |
| SCHEMBL29383469 | 0.79 | AR (0.56) | ARSMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129534-B2 | Chemical compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2012-03-06 | — | — | US | disclosed |