Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346770 | 0.90 | ATM (0.38) | TP53GAABRD4ATMALDH1A1 | |
| SCHEMBL7344138 | 0.89 | GAA (0.42) | TP53GAABRD4ALDH1A1HPGD | |
| SCHEMBL7373035 | 0.89 | ATM (0.35) | TP53GAABRD4ATMAKR1C3 | |
| SCHEMBL7345152 | 0.88 | ATM (0.42) | TP53GAABRD4ATMALDH1A1 | |
| SCHEMBL7347145 | 0.87 | MAPK14 (0.38) | TP53GAABRD4ATMALDH1A1 | |
| SCHEMBL7780810 | 0.87 | TP53 (0.42) | TP53GAABRD4ATMLMNA | |
| SCHEMBL7343921 | 0.86 | CYP19A1 (0.40) | TP53GAABRD4ATMKDM4E | |
| SCHEMBL7344583 | 0.86 | TP53 (0.40) | TP53GAABRD4AKR1C3ALDH1A1 | |
| SCHEMBL7346417 | 0.86 | TP53 (0.42) | TP53GAABRD4ATMLMNA | |
| SCHEMBL7342333 | 0.85 | MEN1 (0.40) | TP53GAABRD4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-B1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-09-05 | — | — | EP | disclosed |
| US-6054457-A | Benzamide derivatives and their use as vasopressin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-25 | — | — | US | disclosed |
| WO-1996041795-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-27 | — | — | WO | disclosed |