Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.67 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337233 | 1.00 | MME (0.67) | MMELTA4HACE | |
| SCHEMBL7337585 | 0.84 | MME (0.74) | MMELTA4HACE | |
| SCHEMBL7337582 | 0.84 | MME (0.74) | MMELTA4HACE | |
| SCHEMBL7335220 | 0.83 | MME (0.68) | MMELTA4HACE | |
| SCHEMBL7335223 | 0.83 | MME (0.68) | MMELTA4HACE | |
| SCHEMBL3063381 | 0.81 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL8166946 | 0.81 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL10954948 | 0.81 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL10952078 | 0.81 | MME (1.00) | MMELTA4HACE | |
| SCHEMBL8861553 | 0.79 | MME (0.63) | MMELTA4HACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0605589-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NATRIURETIC PEPTIDES OR NEUTRAL ENDOPEPTIDASE INHIBITORS FOR TREATING OR PREVENTING MYOINTIMAL PROLIFERATION | SCHERING CORPORATION (US) | 1994-07-13 | — | — | EP | claimed |
| WO-1993005809-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING NATRIURETIC PEPTIDES OR NEUTRAL ENDOPEPTIDASE INHIBITORS FOR TREATING OR PREVENTING MYOINTIMAL PROLIFERATION | SCHERING CORPORATION (US) | 1993-04-01 | — | — | WO | claimed |
| EP-0533084-A1 | Pharmaceutical compositions comprising natriuretic peptides or neutral endopeptidase inhibitors for treating and preventing myointimal proliferation | SCHERING CORPORATION (US) | 1993-03-24 | — | — | EP | claimed |