Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7337250 | 1.00 | GABRR1 (0.41) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL27431345 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL1601477 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL7193017 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL4898850 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL2437343 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL8436474 | 0.77 | GABRR1 (0.42) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL6036741 | 0.76 | SLC1A3 (0.43) | TP53 | |
| SCHEMBL27810909 | 0.76 | GABRR1 (0.48) | GABRR1CYP1A2FOLH1NAALAD2ENPEP | |
| SCHEMBL4908056 | 0.75 | GABRR1 (0.46) | GABRR1CYP1A2FOLH1NAALAD2ENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143747-A | ENZYME INHIBITORS | G. D. SEARLE & CO. (US) | 2000-11-07 | — | — | US | disclosed |
| WO-1996022287-A1 | BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |