Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 9/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561766 | 0.82 | HSD17B3 (0.50) | LMNASMN1; SMN2HSD17B3AVPR2 | |
| SCHEMBL7332478 | 0.76 | AVPR2 (0.67) | AVPR2 | |
| SCHEMBL7333775 | 0.76 | AVPR2 (0.50) | AVPR2 | |
| SCHEMBL9267490 | 0.75 | MEN1 (0.50) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4535815 | 0.75 | AVPR2 (0.71) | AVPR2 | |
| SCHEMBL7345789 | 0.74 | AVPR2 (0.50) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9174371 | 0.74 | MEN1 (0.61) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7019375 | 0.74 | AVPR2 (0.73) | AVPR2 | |
| SCHEMBL6617113 | 0.73 | AVPR2 (0.46) | MAPTAVPR2 | |
| SCHEMBL6988456 | 0.72 | HSD17B3 (0.69) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996022282-A1 | TRICYCLIC BENZAZEPINE VASOPRESSIN ANTAGONISTS | AMERICAN CYANAMID COMPANY (US) | 1996-07-25 | — | — | WO | disclosed |